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Products Details
Product Description
– ERD-3111 (Compound 44), an orally active PROTAC ERα degrader (DC50: 0.5 nM), exhibits efficacy in inhibiting tumor growth in both the parental MCF-7 xenograft model harboring wild-type ER and two ESR1-mutated mouse models. This compound has utility in the investigation of ER+ breast cancer [1].
Web ID
– T78824
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C45H46F4N8O5
CAS Number
– 2832865-25-3
Molecular Weight
– C45H46F4N8O5
SMILES
– C(C(F)F)N1[C@@H](C2=C(C3=C(C=C2)NN=C3)C[C@H]1C)C4=C(F)C=C(C=C4F)N5CCC6(CC5)CCN(C(CN7CC=8C(C7)=CC9=C(C8)C(=O)N(C9=O)C%10C(=O)NC(=O)CC%10)=O)CC6
Pathway
– Endocrinology/Hormones
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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