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Products Details
Product Description
– HDAC6 degrader-1, a proteolysis-targeting chimeric molecule (PROTAC), incorporates the selective HDAC6 inhibitor Nexturastat A (Nex A) for HDAC6 binding, a linker, and an E3 ligase recruiting ligand. This compound effectively induces HDAC6 degradation, displays superior selectivity over other HDAC isoforms, and efficiently inhibits cell proliferation [1].
Web ID
– T77922
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C40H45N9O9
CAS Number
– 2439058-23-6
Molecular Weight
– C40H45N9O9
SMILES
– O=C(NO)C1=CC=C(C=C1)CN(C(=O)NC=2C=CC=CC2)CCCCC=3N=NN(C3)CCOCCOCCNC4=CC=CC=5C(=O)N(C(=O)C45)C6C(=O)NC(=O)CC6
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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