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(Aminooxy)acetamide-Val-Cit-PAB-MMAE
Products Details
Product Description
– (Aminooxy)acetamide-Val-Cit-PAB-MMAE (MMAE 5) serves as an intermediate for synthesizing drug-linker conjugates in antibody-drug conjugates (ADCs). The compound is initially conjugated to a polyamide via oxime bond formation, forming an MMAE polyamide conjugate, which is then attached to Trastuzumab to create the ADC [1].
Web ID
– T77885
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C60H97N11O14
CAS Number
– 2446645-88-9
Molecular Weight
– C60H97N11O14
SMILES
– [C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC([C@@H](NC([C@@H](NC(CON)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C3)=O)C)C(C)C)=O)[C@@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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