Ascrinvacumab

SKU T76858-1 mg Category Brand:

Price range: 315 CAD through 2,608 CAD

Products Details

Product Description

– Ascrinvacumab (PF-03446962) is a highly humanized IgG2 monoclonal antibody against ALK-1 with a Kd value of 7 nM for human ALK1. It has an inhibitory effect on TGF-β and can be used to study hepatocellular carcinoma (HCC).

Web ID

– T76858

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– van Meeteren LA, et al. Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sprouting. J Biol Chem. 2012 May 25;287(22):18551-61.

CAS Number

– 1463459-96-2

Molecular Weight

Compound Purity

– 98.18% (SEC-HPLC)

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis|||Stem Cells

Product type

– Inhibitory Antibodies

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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