KTX-582
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KTX-582

SKU T74664-5 mg Category Brand:

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Product Description

– KTX-582 is a potent IRAK4 degrader with DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. It effectively induces apoptosis in MYD88 MT DLBCL and has demonstrated efficacy in inducing in vivo tumor regressions in a lymphoma model [1] [2] [3].

Web ID

– T74664

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C45H51F3N8O7

CAS Number

– 2573298-13-0

Molecular Weight

– C45H51F3N8O7

SMILES

– CN(CCCO[C@H]1C[C@@H](C1)Nc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12)C[C@H]1CC[C@@H](CC1)n1cc2cc(NC(=O)c3cccc(n3)C(F)(F)F)c(cc2n1)C(C)(C)O

Pathway

– PROTAC

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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