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Products Details
Product Description
– SS47, a PROTAC-based HPK1 degrader, induces proteasome-mediated HPK1 degradation and significantly enhances the in vivo antitumor efficacy of BCMA CAR-T cell research. HPK1, an immunosuppressive regulatory kinase, is a promising target for cancer immunotherapies [1].
Web ID
– T74508
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C49H56N6O12S
CAS Number
– 2636072-62-1
Molecular Weight
– C49H56N6O12S
SMILES
– O=C1C=2C=CC=C(OCCOCCOCCOCCOCCC(=O)N3CCC(C4=NC=C(S4)C=5C=NC(N)=C(OCC=6C=CC=C(C#CC(O)(C)C)C6)C5)CC3)C2C(=O)N1C7C(=O)NC(=O)CC7
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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