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Products Details
Product Description
– JPS035, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), specifically HDAC1/2. Its potent activity is associated with an increase in differentially expressed genes and enhanced apoptosis in HCT116 cells [1].
Web ID
– T74455
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C49H65N7O7S
CAS Number
– 2669785-84-4
Molecular Weight
– C49H65N7O7S
SMILES
– CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1OCCCCCCCCCCCC(=O)Nc1ccc(cc1)C(=O)Nc1ccccc1N)-c1scnc1C)C(C)(C)C
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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