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ARS-853
Price range: 245 CAD through 5,488 CAD
Products Details
Product Description
– ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells
Web ID
– T7414
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H29ClN4O3
References
– Lito P , Solomon M , Li L S , et al. Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism[J]. Science, 2016:science.aad6204.
CAS Number
– 1629268-00-3
Molecular Weight
– C22H29ClN4O3
Compound Purity
– 0.984
SMILES
– CC1(CC1)c1cc(NCC(=O)N2CCN(CC2)C2CN(C2)C(=O)C=C)c(O)cc1Cl
Pathway
– MAPK|||Apoptosis|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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