Abemaciclib metabolite M18

SKU T73909-5 mg Category Brand:

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Products Details

Product Description

– Abemaciclib metabolite M18 (LSN3106729) is a potent cyclin-dependent kinase (CDK) inhibitor with antitumor properties. It has been incorporated alongside a cereblon (CRBN) ligand to develop a proteolysis-targeting chimera (PROTAC) that selectively degrades CDK4/6 [1] [2].

Web ID

– T73909

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H28F2N8O

CAS Number

– 2704316-81-2

Molecular Weight

– C25H28F2N8O

SMILES

– C(C)(C)N1C=2C(N=C1CO)=C(F)C=C(C2)C3=NC(NC4=CC=C(CN5CCNCC5)C=N4)=NC=C3F

Pathway

– PROTAC

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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