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EB1
Price range: 109 CAD through 5,584 CAD
Products Details
Product Description
– EB1 is a potent and selective MNK kinase inhibitor with inhibitory effects on MNK1 and MNK2 with IC50 values of 0.69 μM and 9.4 μM, respectively.EB1 inhibits the growth of cancer cells, promotes apoptosis, and inhibits the phosphorylation of eIF4E.
Web ID
– T73582
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H14N4
References
– Aboukhatwa SM, et al. Nicotinonitrile-derived apoptotic inducers: Design, synthesis, X-ray crystal structure and Pim kinase inhibition. Bioorg Chem. 2022 Dec;129:106126.
CAS Number
– 42951-68-8
Molecular Weight
– C18H14N4
Compound Purity
– 0.9982
SMILES
– NC=1C2=C(C=C(N=C2NN1)C3=CC=CC=C3)C4=CC=CC=C4
Pathway
– MAPK
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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