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Ionomycin
314 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– Ionomycin is an calcium ionophore and an antibiotic that binds calcium ions (Ca2+). It is produced by the bacterium Streptomyces conglobatus.It is used in research to raise the intracellular calcium level (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes. Ionomycin promotes apoptosis and induces the activation of protein kinase C (PKC).
Web ID
– T7285
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C41H72O9
Citations
– 1. Zhang Y, Shi Q, Wang P, et al.iPSC‐derived NK cells with site‐specific integration of CAR19 and IL24 at the multi‐copy rDNA locus enhanced antitumor activity and proliferation.MedComm.2024, 5(5): e553.
2. Zhao X, Zhao Z, Li B, et al.ACSL4-mediated lipid rafts prevent membrane rupture and inhibit immunogenic cell death in melanoma.Cell Death & Disease.2024, 15(9): 695.
References
– Lautens M, et al. Total synthesis of ionomycin using ring-opening strategies. Org Lett. 2002 May 30;4(11):1879-82.
CAS Number
– 56092-81-0
Molecular Weight
– C41H72O9
Compound Purity
– 0.9954
SMILES
– [H][C@@]1(C[C@H](O)[C@H](C)[C@H](O)[C@H](C)C=CC[C@@H](C)C[C@@H](C)C(O)=CC(=O)[C@@H](C)C[C@@H](C)C[C@H](C)CCC(O)=O)CC[C@](C)(O1)[C@@]1([H])CC[C@](C)(O1)[C@@H](C)O
Pathway
– Membrane transporter/Ion channel|||Metabolism
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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