Desmethyl Erlotinib hydrochloride

SKU T6619-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 86 CAD through 1,213 CAD

Products Details

Product Description

– Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells.

Web ID

– T6619

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H21N3O4·HCl

References

– Meany HJ, et al. Cancer Chemother Pharmacol. 2008, 62(3), 387-392.

CAS Number

– 183320-51-6

Molecular Weight

– C21H21N3O4·HCl

Compound Purity

– 0.9949

SMILES

– Cl.COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCO

Pathway

– Angiogenesis|||Metabolism|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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