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Dolutegravir
Price range: 48 CAD through 1,872 CAD
Products Details
Product Description
– Dolutegravir (GSK1349572) (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Web ID
– T6198
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H19F2N3O5
Citations
– 1. Herrmann A, Roesner M, Werner T, et al. Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin. Scientific Reports. 2020, 10(1): 1-15
References
– Charpentier C, et al. AIDS. 2010, 24(17), 2753-275
CAS Number
– 1051375-16-6
Molecular Weight
– C20H19F2N3O5
Compound Purity
– 0.9908
SMILES
– C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12
Pathway
– Proteases/Proteasome|||Microbiology/Virology
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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