Download Files:
Birinapant
Price range: 66 CAD through 795 CAD
Products Details
Product Description
– Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity.
Web ID
– T6007
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C42H56F2N8O6
Citations
– 1. Bhatt S, Pioso M S, Olesinski E A, et al. Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia. Cancer Cell. 2020, 38(6): 872-890. e6.
2. Olesinski E A, Bhatia K S, Wang C, et al.Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in Relapsed Myeloblasts.Blood Cancer Discovery.2024: OF1-OF22.
References
– Allensworth JL, et al. Breast Cancer Res Treat, 2013, 137(2), 359-371.
CAS Number
– 1260251-31-7
Molecular Weight
– C42H56F2N8O6
Compound Purity
– 0.9978
SMILES
– CC[C@H](NC(=O)[C@H](C)NC)C(=O)N1C[C@@H](O)C[C@H]1Cc1c([nH]c2cc(F)ccc12)-c1[nH]c2cc(F)ccc2c1C[C@@H]1C[C@H](O)CN1C(=O)[C@H](CC)NC(=O)[C@H](C)NC
Pathway
– Apoptosis|||Microbiology/Virology|||Proteases/Proteasome
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
1000 in stock
