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DMX-5804
Price range: 173 CAD through 2,048 CAD
Products Details
Product Description
– DMX-5804 is a potent, selective MAP4K4 inhibitor, with an IC50 of 3 nM.DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice.
Web ID
– T5483
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H19N3O3
Citations
– 1. Zhang Z, Zhou H, Gu W, et al.CGI1746 targets σ1R to modulate ferroptosis through mitochondria-associated membranes.Nature Chemical Biology.2024: 1-11.
References
– Fiedler LR, et al. MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo. Cell Stem Cell. 2019 Mar 1. pii: S1934-5909(19)30013-X.
CAS Number
– 2306178-56-1
Molecular Weight
– C21H19N3O3
Compound Purity
– 0.9934
SMILES
– COCCOc1ccc(cc1)-c1cn(-c2ccccc2)c2nc[nH]c(=O)c12
Pathway
– MAPK
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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