Download Files:
BIX 02565
Price range: 122 CAD through 571 CAD
Products Details
Product Description
– BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).
Web ID
– T5428
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H30N6O2
Citations
– 1. Yuan Y, Xu J, Jiang L, et al. Discovery, Optimization, and Structure–Activity Relationship Study of Novel and Potent RSK4 Inhibitors as Promising Agents for the Treatment of Esophageal Squamous Cell Carcinoma. Journal of Medicinal Chemistry. 2021
References
– Kirrane TM, et al. Indole RSK inhibitors. Part 2: optimization of cell potency and kinase selectivity. Bioorg Med Chem Lett. 2012 Jan 1;22(1):738-42.
CAS Number
– 1311367-27-7
Molecular Weight
– C26H30N6O2
Compound Purity
– 0.9961
SMILES
– C[C@@H]1CCNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc2ccccc2n1CCCN(C)C
Pathway
– MAPK|||Autophagy|||PI3K/Akt/mTOR signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
