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Halazone
$45 – $100
Products Details
Product Description
– Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 µM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water[1][2].
Web ID
– HY-B1386
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C7H5Cl2NO4S
References
– [1]M Rack, et al. Effects of Some Chemical Reagents on Sodium Current Inactivation in Myelinated Nerve Fibers of the Frog. Biophys J. 1986 Oct;50(4):557-64.|[2]Rema Iyer, et al. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. J Biomol Screen. 2006 Oct;11(7):782-91.
CAS Number
– 80-13-7
Molecular Weight
– 270.09
Compound Purity
– 75.0
SMILES
– O=C(O)C1=CC=C(S(=O)(N(Cl)Cl)=O)C=C1
Clinical Information
– Launched
Research Area
– Infection
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Bacterial;Carbonic Anhydrase;Sodium Channel
Isoform
– CA â…¡
Pathway
– Anti-infection;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
