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ARD-61
2,432 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– ARD-61 is a potent and specific PROTAC androgen receptor (AR) degrader, exhibiting high effectiveness. It effectively induces the degradation of AR and progesterone receptors (PR) in AR+ cancer cell lines, leading to apoptosis. Additionally, ARD-61 demonstrates significant tumor growth inhibition in the MDA-MB-453 xenograft model in mice.
Web ID
– T39853
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C61H71ClN8O7S
References
– Lijie Zhao, et al. A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo. Neoplasia. 2020 Oct;22(10):522-532.
CAS Number
– 2316837-08-6
Molecular Weight
– C61H71ClN8O7S
SMILES
– CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](CC(=O)N1CCC(CC1)N1CCC(CC1)C#Cc1ccc(cc1)C(=O)N[C@H]1C(C)(C)[C@H](Oc2ccc(C#N)c(Cl)c2)C1(C)C)c1ccc(cc1)-c1scnc1C)c1cc(C)no1
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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