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Products Details
Product Description
– Thalidomide-NH-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate containing a cereblon ligand derived from Thalidomide and a linker used in the synthesis of MI-389 [compound 22], a highly effective phthalimide PROTAC degrader developed from the multi-targeted receptor tyrosine kinase inhibitor sunitinib.
Web ID
– T39512
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H32N4O6
References
– Mette Ishoey, et al. Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders.ACS Chem Biol. 2018 Mar 16;13(3):553-560.
CAS Number
– 2093536-13-9
Molecular Weight
– C24H32N4O6
SMILES
– CC(C)(C)OC(=O)NCCCCCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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