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Products Details
Product Description
– Ipatasertib-NH2 dihydrochloride is a ligand for the target protein AKT in PROTAC [INY-03-041], comprising Ipatasertib-NH2, a ten-hydrocarbon linker, and the CRBN ligand Lenalidomide, which functions as an E3 ubiquitin ligase.
Web ID
– T38393
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H28Cl3N5O2
References
– You I, et al. Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling. Cell Chem Biol. 2020 Jan 16;27(1):66-73.e7.
CAS Number
– 1001264-73-8
Molecular Weight
– C21H28Cl3N5O2
SMILES
– Cl.Cl.C[C@@H]1C[C@@H](O)c2ncnc(N3CCN(CC3)C(=O)[C@H](CN)c3ccc(Cl)cc3)c12
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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