Desmethyl Bosentan

SKU T37351-1 mg Category Brand:

Price range: 474 CAD through 3,840 CAD

Products Details

Product Description

– Desmethyl bosentan, an active metabolite of the endothelin receptor antagonist bosentan, activates the pregnane X receptor (PXR) in CV-1 monkey kidney cells expressing the human receptor in a reporter assay at a concentration of 25 μM.

Web ID

– T37351

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H27N5O6S

References

– van Giersbergen, P.L.M., Gnerre, C., Treiber, A., et al.Bosentan, a dual endothelin receptor antagonist, activates the pregnane X nuclear receptorBr. J. Clin. Pharmacol.54(5)561-562(2002)

CAS Number

– 253688-61-8

Molecular Weight

– C26H27N5O6S

SMILES

– CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1nc(nc(OCCO)c1Oc1ccccc1O)-c1ncccn1

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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