Fanotaprim

SKU T36692-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 1,501 CAD

Products Details

Product Description

– Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor, suppressing the growth of T. gondii strains with a TgDHFR IC50 of 1.57 ± 0.11 nM, a hDHFR IC50 of 308 ± 71 nM, and a hDHFR to TgDHFR selectivity ratio of 196.

Web ID

– T36692

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H22N8O

References

– Hopper AT, et al. Discovery of Selective Toxoplasma gondii Dihydrofolate Reductase Inhibitors for the Treatment of Toxoplasmosis. J Med Chem. 2019;62(3):1562-1576.

CAS Number

– 2120282-75-7

Molecular Weight

– C19H22N8O

Compound Purity

– 0.9737

SMILES

– COc1ncc(cn1)-c1cccc(c1)N1CCN(CC1)c1cnc(N)nc1N

Pathway

– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Metabolism

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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