Gliovirin

SKU T35741-1 mg Category Brand:

1,107 CAD

Only 1000 item(s) left in stock.

Products Details

Product Description

– Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decreases phorbol 12-myristate 13-acetate (TPA)- and ionomycin-induced increased expression of COX-2 (IC50= 1 μM) and protein levels of IL-2 in Jurkat cells (IC50= 5.2 μM).1

Web ID

– T35741

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H20N2O8S2

References

– Rether, J., Serwe, A., Anke, T., et al.Inhibition of inducible tumor necrosis factor-α expression by the fungal epipolythiodiketopiperazine gliovirinBiol. Chem.388(6)627-637(2007)

CAS Number

– 83912-90-7

Molecular Weight

– C20H20N2O8S2

SMILES

– COc1ccc(C2SSC34CC56OC5C=CC(O)C6ON3C(=O)C2NC4=O)c(O)c1OC

Target

– Others

Pathway

– Others

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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