(E/Z)-THZ1 2HCl

SKU T35332-1 mg Category Brand:

Price range: 64 CAD through 1,595 CAD

Products Details

Product Description

– THZ1 2HCl (THZ1 Dihydrochloride) is a selective, covalent, and allosteric inhibitor of CDK7 with an IC50 of 3.2 nM. THZ1 2HCl has antiproliferative effects on a variety of cancer cell lines.

Web ID

– T35332

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H30Cl3N7O2

References

– Kwiatkowski N, et al. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor. Nature. 2014 Jul 31;511(7511):616-20.

CAS Number

– 2095433-94-4

Molecular Weight

– C31H30Cl3N7O2

Compound Purity

– 0.9833

SMILES

– Cl.Cl.CN(C)CC=CC(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1

Target

– Others

Pathway

– Cell Cycle/Checkpoint

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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