Dasabuvir

SKU T3489-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 53 CAD through 590 CAD

Products Details

Product Description

– Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase. Upon administration and intracellular uptake, dasabuvir binds HCV NS5B polymerase, blocking viral RNA synthesis and replication. The HCV NS5B protein is essential for the replication of the HCV RNA genome.

Web ID

– T3489

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H27N3O5S

Citations

– 1. Hayashi T, Murakami K, Hirano J, et al. Dasabuvir inhibits human norovirus infection in human intestinal enteroids. mSphere. 2021, 6(6): e00623-21.

References

– Kati W, et al. In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor. Antimicrob Agents Chemother. 2015 Mar;59(3):1505-11.

CAS Number

– 1132935-63-7

Molecular Weight

– C26H27N3O5S

Compound Purity

– 0.9962

SMILES

– COc1c(cc(cc1C(C)(C)C)-n1ccc(=O)[nH]c1=O)-c1ccc2cc(NS(C)(=O)=O)ccc2c1

Target

– Apoptosis

Pathway

– Microbiology/Virology|||Proteases/Proteasome

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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