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Dasabuvir
53 CAD – 590 CADPrice range: 53 CAD through 590 CAD
Products Details
Product Description
– Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase. Upon administration and intracellular uptake, dasabuvir binds HCV NS5B polymerase, blocking viral RNA synthesis and replication. The HCV NS5B protein is essential for the replication of the HCV RNA genome.
Web ID
– T3489
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H27N3O5S
Citations
– 1. Hayashi T, Murakami K, Hirano J, et al. Dasabuvir inhibits human norovirus infection in human intestinal enteroids. mSphere. 2021, 6(6): e00623-21.
References
– Kati W, et al. In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor. Antimicrob Agents Chemother. 2015 Mar;59(3):1505-11.
CAS Number
– 1132935-63-7
Molecular Weight
– C26H27N3O5S
Compound Purity
– 0.9962
SMILES
– COc1c(cc(cc1C(C)(C)C)-n1ccc(=O)[nH]c1=O)-c1ccc2cc(NS(C)(=O)=O)ccc2c1
Target
– Apoptosis
Pathway
– Microbiology/Virology|||Proteases/Proteasome
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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