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Maralixibat (chloride)
$390 – $4,960
Products Details
Product Description
– Maralixibat (SHP625) chloride is an orally active ileal bile acid transporter (IBAT) inhibitor. Maralixibat chloride can be used for the research of rare cholestatic liver diseases including Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC) and biliary atresia[1][2].
Web ID
– HY-16747
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C40H56ClN3O4S
References
– [1]Shirley M. Maralixibat: First Approval [published correction appears in Drugs. 2021 Dec 6;:]. Drugs. 2022;82(1):71-76.|[2]Mayo MJ, et al. A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. Hepatol Commun. 2019 Feb 1;3(3):365-381.
CAS Number
– 228113-66-4
Molecular Weight
– 710.41
Compound Purity
– 99.08
SMILES
– O=S1(CC(CCCC)(CCCC)[C@H](O)[C@H](C2=CC=C(OCC3=CC=C(C[N+]4(CC5)CCN5CC4)C=C3)C=C2)C6=CC(N(C)C)=CC=C61)=O.[Cl-]
Clinical Information
– Launched
Research Area
– Metabolic Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Apical Sodium-Dependent Bile Acid Transporter
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
