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GRC-17536
2,432 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– GRC-17536 is an orally available, potent, and selective transient receptor potential anchor protein 1 (TRPA1) inhibitor that has been shown to be highly effective in the treatment of inflammation and neuropathic pain in animal models. The selectivity of GRC-17536 is more than 1000 times higher than that of other TRPs, numerous GPCRs, enzymes, and other ion channels.
Web ID
– T31995
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H12F5KN4O3S2
References
– Mukhopadhyay I, Kulkarni A, Aranake S, Karnik P, Shetty M, Thorat S, Ghosh I, Wale D, Bhosale V, Khairatkar-Joshi N. Transient receptor potential ankyrin 1 receptor activation in vitro and in vivo by pro-tussive agents: GRC 17536 as a promising anti-tussive therapeutic. PLoS One. 2014 May 12;9(5):e97005. doi: 10.1371/journal.pone.0097005. eCollection 2014. PubMed PMID: 24819048; PubMed Central PMCID: PMC4018403.
CAS Number
– 1649479-05-9
Molecular Weight
– C20H12F5KN4O3S2
SMILES
– Cn(c(scc1CC([N-]c2scc(c3c(F)c(C(F)(F)F)c(F)cc3)n2)=O)c1c(=O)n4C)c4=O.[K+]
Target
– Others
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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