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Products Details
Product Description
– Tubulin inhibitor 31 is a potent tubulin inhibitor with an IC50 value of 4 µM. Tubulin inhibitor 31 shows anti-proliferative activity. Tubulin inhibitor 31 inhibits the HUVEC migration[1].
Web ID
– HY-151996
Shipping
– Room temperature
Molecular Formula
– C22H19NO2
References
– [1]Prudhomme V, et al. Design, synthesis and biological evaluation of conformationnally-restricted analogues of E7010 as inhibitors of tubulin assembly (ITA) and vascular disrupting agents (VDA). Eur J Med Chem. 2022 Dec 15;244:114809.
Molecular Weight
– 329.39
SMILES
– COC1=CC=C(C=C1)CN2C=C(C3=C2C=CC=C3)C4=CC=C(C=C4)O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
