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S1PR1 Radioligand 1

SKU HY-149210-Get quote Category Tags , ,

Products Details

Product Description

– S1PR1 Radioligand 1(compound 6 h) is a specific S1PR1 radioligand with IC50 = 8.7 nM. S1PR1 Radioligand 1 has good brain uptake and can be used as a S1PR1-specific F-18 radiotracer for studying the function of S1PR1 in brain diseases[1].

Web ID

– HY-149210

Shipping

– Room temperature

Molecular Formula

– C22H22F5N3O3

References

– [1]Lin Qiu, et al. Discovery of a Promising Fluorine-18 Positron Emission Tomography Radiotracer for Imaging Sphingosine-1-Phosphate Receptor 1 in the Brain. J Med Chem. 2023 Mar 16. 

CAS Number

– 2845249-11-6

Molecular Weight

– 471.42

SMILES

– CN(CC1=C(C=C(C=C1)C2=NOC(C3=CC(C(F)(F)F)=C(C=C3)OCCF)=N2)F)CCCO

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– LPL Receptor

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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