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GS-9191
Price range: 173 CAD through 2,432 CAD
Products Details
Product Description
– GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetrates the skin and is metabolized in the epithelium to an active nucleoside triphosphate analogue.GS-9191 has antiproliferative activity and reduces the size of papillomas in a dose-related manner.GS-9191 may be useful in the treatment of HPV-induced lesions.
Web ID
– T25466
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C37H51N8O6P
References
– Birkus G, et al. Role of cathepsin A and lysosomes in the intracellular activation of novel antipapillomavirus agent GS-919Antimicrob Agents Chemother. 2011;55(5):2166-73.
CAS Number
– 859209-84-0
Molecular Weight
– C37H51N8O6P
Compound Purity
– 0.9828
SMILES
– C(COCP(N[C@@H](CC1=CC=CC=C1)C(OCC(C)C)=O)(N[C@@H](CC2=CC=CC=C2)C(OCC(C)C)=O)=O)N3C=4C(=C(NC5CC5)N=C(N)N4)N=C3
Pathway
– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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