GS143
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GS143

SKU T25465-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 51 CAD through 923 CAD

Products Details

Product Description

– GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. It suppresses NF-κB activation and transcription of target genes without inhibiting proteasome activity. GS143 has anti-asthm[atic] properties.

Web ID

– T25465

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H19FN2O4

References

– Rashmi BS, Gayathri D. Molecular characterization of gluten hydrolysing Bacillus sp. and their efficacy and biotherapeutic potential as probiotics using Caco-2 cell line. J Appl Microbiol. 2017 Sep;123(3):759-772. doi: 10.1111/jam.13517. Epub 2017 Aug 4. PubMed PMID: 28637081.

CAS Number

– 916232-21-8

Molecular Weight

– C28H19FN2O4

Compound Purity

– 0.9767

SMILES

– OC(=O)c1ccc(cc1)N1N=C(Cc2ccccc2)C(=C/c2ccc(o2)-c2ccccc2F)C1=O

Pathway

– NF-κB|||Ubiquitination

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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