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Nesbuvir
$355 – $1,800
Products Details
Product Description
– Nesbuvir is a nonnucleoside inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase.
Web ID
– HY-14775
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C22H23FN2O5S
References
– [1]Flint M, et al. Selection and characterization of hepatitis C virus replicons dually resistant to the polymerase and protease inhibitors HCV-796 and boceprevir (SCH 503034).
Antimicrob Agents Chemother. 2009 Feb;53(2):401-11.|[2]Reich S, et al. Mechanisms of activity and inhibition of the hepatitis C virus RNA-dependent RNA polymerase.
J Biol Chem. 2010 Apr 30;285(18):13685-93.
CAS Number
– 691852-58-1
Molecular Weight
– 446.49
Compound Purity
– 98.83
SMILES
– O=C(C1=C(C2=CC=C(F)C=C2)OC3=CC(N(CCO)S(=O)(C)=O)=C(C4CC4)C=C13)NC
Clinical Information
– Phase 2
Research Area
– Infection
Solubility
– DMSO : ≥ 50 mg/mL
Target
– HCV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
