Efavirenz
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Efavirenz

SKU T2393-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 56 CAD through 680 CAD

Products Details

Product Description

– Efavirenz (DMP 266) is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor, acting as a Non-Nucleoside Reverse Transcriptase Inhibitor, Cytochrome P450 3A Inducer, Cytochrome P450 2B6 Inducer, Cytochrome P450 2C9 Inhibitor, Cytochrome P450 2C19 Inhibitor, and Cytochrome P450 3A4 Inhibitor, classified as a Non-Nucleoside Analog.

Web ID

– T2393

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H9ClF3NO2

Citations

– 1. Cheng C, Ji Z, Sheng Y, et al. Aphthous ulcer drug inhibits prostate tumor metastasis by targeting IKKɛ/TBK1/NF-κB signaling. Theranostics. 2018, 8(17): 4633 2. Zhang R, Zhang F, Sun Z, et al. LINE-1 Retrotransposition Promotes the Development and Progression of Lung Squamous Cell Carcinoma by Disrupting the Tumor Suppressor Gene FGGY. Cancer Research. 2019: canres. 0076 3. Wu Y, Chu L, Yang H, et al. Simultaneous Determination of 6 Antiretroviral Drugs in Human Hair Using an LC-ESI+-MS/MS Method: Application to Adherence Assessment. Therapeutic Drug Monitoring. 2021, 43(6): 756-765.

References

– Braz VA, et al. Biochemistry. 2010, 49(3):601-10.

CAS Number

– 154598-52-4

Molecular Weight

– C14H9ClF3NO2

Compound Purity

– 0.9983

SMILES

– C(#CC1CC1)[C@@]2(C(F)(F)F)C=3C(NC(=O)O2)=CC=C(Cl)C3

Pathway

– Autophagy|||Proteases/Proteasome|||Microbiology/Virology

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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