GSK-114

SKU T22341-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 1,059 CAD

Products Details

Product Description

– GSK-114 is a selective inhibitor of TNNI3 interacting kinase (TNNI3K) with an IC50 of 25 nM, 40-fold significant bias for TNNI3K compared to B-Raf with an IC50 of 1000 nM, so GSK-114 has excellent Broad-spectrum kinase selectivity and sufficient oral exposure enable use in cellular and in vivo studies.

Web ID

– T22341

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H23N5O4S

References

– Brian G. Lawhorna, Joanne Philpa, et al. GSK114: A selective inhibitor for elucidating the biological role of TNNI3K. Bioorganic & Medicinal Chemistry Letters. Volume 26, Issue 14, 15 July 2016, Pages 3355-3358

CAS Number

– 1301761-96-5

Molecular Weight

– C19H23N5O4S

Compound Purity

– 0.9966

SMILES

– CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OC)c(OC)cc23)c1

Target

– Others

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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