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LDN-212854
Price range: 67 CAD through 1,680 CAD
Products Details
Product Description
– LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors; possesses differences towards ALK2(IC50=1.3 nM) versus ALK1/3 compared to other inhibitors.
Web ID
– T1900
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H22N6
Citations
– 1. Yuan Q, Cao S, Dong Q, et al. ALDH2 Activation Inhibited Cardiac Fibroblast-to-Myofibroblast Transformation Via the TGF-β1/Smad Signaling Pathway. Journal of cardiovascular pharmacology. 2019 Apr;73(4): 248-256.
References
– ACS Chem Biol. 2013, 8(6), 1291-1302.
CAS Number
– 1432597-26-6
Molecular Weight
– C25H22N6
Compound Purity
– 0.9938
SMILES
– C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1cccc2ncccc12
Target
– ALK|||TGF-beta/Smad
Pathway
– Stem Cells|||Angiogenesis|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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