Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride

SKU T18820-100 mg Category Brand:

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Products Details

Product Description

– Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, incorporates a cereblon ligand derived from Thalidomide and a 3-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes small molecules to induce protein degradation [1].

Web ID

– T18820

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H31ClN4O9

References

– Methods to induce targeted protein degradation through bifunctional molecules. WO2017007612A1.

CAS Number

– 2245697-84-9

Molecular Weight

– C23H31ClN4O9

SMILES

– Cl.O=C(NCCOCCOCCOCCN)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

Target

– Others

Pathway

– Others

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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