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CMPD-39
$180 – $2,950
Products Details
Product Description
– CMPD-39 is a selective USP30 inhibitor with an IC50 of 0.02 μM. CMPD-39 increases protein ubiquitination and accelerates mitophagy[1].
Web ID
– HY-141659
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H28FN3O4S
References
– [1]Arthur F Kluge, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg Med Chem Lett. 2018 Aug 15;28(15):2655-2659.|[2]Rusilowicz-Jones EV, Barone FG, Lopes FM, et al. Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy. Life Sci Alliance. 2021;5(2):e202101287.
CAS Number
– 2242582-40-5
Molecular Weight
– 497.58
Compound Purity
– 99.82
SMILES
– CC(C)(C)NS(=O)(C1=CC=C(C=C1)NC([C@@H](NC(C2=CC=C(C=C2)F)=O)CC3=CC=CC=C3)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Deubiquitinase
Isoform
– USP30
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
