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E 2012
Price range: 54 CAD through 317 CAD
Products Details
Product Description
– E2012 is a γ-secretase modulator (GSM). E2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer’s disease by reduction of amyloid β-42, and induces cataract following repeated doses in the rat.
Web ID
– T15184
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H26FN3O2
References
– Nakano-Ito K, et al. E2012-induced cataract and its predictive biomarkers. Toxicol Sci. 2014 Jan;137(1):249-58.
CAS Number
– 870843-42-8
Molecular Weight
– C25H26FN3O2
Compound Purity
– 0.9918
SMILES
– COc1cc(C=C2/CCCN([C@@H](C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1
Target
– Others
Pathway
– Neuroscience|||Stem Cells|||Proteases/Proteasome
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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