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Purmorphamine
Price range: 82 CAD through 475 CAD
Products Details
Product Description
– Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo. It also is an inducer of osteoblast differentiation.
Web ID
– T1810
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C31H32N6O2
Citations
– 1. Singh K, Nawabjan S A, Zhang L, et al. Discovery of small-molecule modulators of the secretin receptor: Purmorphamine as novel anti-hypertensive agent. European Journal of Medicinal Chemistry. 2022: 114642.
2. Mendonça L S, Henriques D, Fernandes V, et al.Graft-derived neurons and bystander effects are maintained for six months after human iPSC-derived NESC transplantation in mice’s cerebella.Scientific Reports.2024, 14(1): 3236.
References
– Sinha S, et al. Nat Chem Biol, 2006, 2(1), 29-30.
CAS Number
– 483367-10-8
Molecular Weight
– C31H32N6O2
Compound Purity
– 0.9811
SMILES
– C1CCC(CC1)n1cnc2c(Nc3ccc(cc3)N3CCOCC3)nc(Oc3cccc4ccccc34)nc12
Target
– Others
Pathway
– Autophagy|||Stem Cells|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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