Download Files:
DM4
Price range: 50 CAD through 717 CAD
Products Details
Product Description
– DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
Web ID
– T15141
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C38H54ClN3O10S
References
– Tang R, et al. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer. 2009 Jun 23;9:199.
CAS Number
– 796073-69-3
Molecular Weight
– C38H54ClN3O10S
Compound Purity
– 0.9815
SMILES
– CO[C@@H]1C=C/C=C(C)Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)S)[C@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2
Target
– Others
Pathway
– Antibody-drug Conjugate/ADC Related|||Cytoskeletal Signaling
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
CDK ligand for PROTAC hydrochloride
Price range: 498 CAD through 3,170 CAD
1000 in stock
1000 in stock
