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Mal-PEG8-Val-Cit-PAB-MMAE
$320 – $1,500
Products Details
Product Description
– Mal-PEG8-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Mal-PEG8-Val-Cit-PAB-MMAE contains a cleavable ADC linker and a potent tubulin inhibitor MMAE (HY-15162)[1].
Web ID
– HY-141156
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C81H131N11O23
References
– [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
CAS Number
– 2353409-69-3
Molecular Weight
– 1626.97
Compound Purity
– 99.67
SMILES
– CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCN4C(C=CC4=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 110 mg/mL (ultrasonic)
Target
– Drug-Linker Conjugates for ADC
Isoform
– Auristatin
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
