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Product Description
– Gemcitabine-O-Si(di-iso)-O-Mc, a drug-linker conjugate for Antibody-Drug Conjugates (ADC), exhibits potent antitumor activity. It incorporates Gemcitabine, a pyrimidine nucleoside analog antimetabolite and antineoplastic agent, connected through the ADC linker [1].
Web ID
– T17985
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H36F2N4O7Si
References
– Mathew C. Finniss, et al. A versatile acid-labile linker for antibody–drug conjugate. MedChemComm, Issue 9, 2014.
Molecular Weight
– C24H36F2N4O7Si
SMILES
– NC(C=CN1[C@H]2C(F)([C@@H]([C@H](O2)CO[Si](C(C)C)(OCCCCCN3C(C=CC3=O)=O)C(C)C)O)F)=NC1=O
Target
– Others
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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