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Products Details
Product Description
– ERRα Ligand-Linker Conjugates 1 refers to a chemical compound that consists of a ligand targeting estrogen-related receptor alpha (ERRα), and a PROTAC linker that facilitates the recruitment of E3 ligases MDM2. It finds utility in the synthesis of a range of PROTACs, including one known as PROTAC ERRalpha Degrader-1. With its capability to induce degradation of ERRα, PROTAC ERRalpha Degrader-1 functions as an ERRα degrader[1].
Web ID
– T17941
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H20F9N3O5
References
– Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.
Molecular Weight
– C24H20F9N3O5
SMILES
– NCCNC(/C(C#N)=C/C1=CC(OC)=C(C=C1)OCC2=C(C(F)(F)F)C=C(C(F)(F)F)C=C2)=O.O=C(C(F)(F)F)O
Target
– CDK|||PKA|||Akt|||PKC|||ERK
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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