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E3 ligase Ligand 8
Price range: 46 CAD through 365 CAD
Products Details
Product Description
– E3 ligase Ligand 8, a ligand for E3 ubiquitin ligase, can be connected to protein ligands through linkers to form PROTACs, which induce ubiquitination-mediated degradation of cancer-promoting proteins.
Web ID
– T17879
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C31H34N2O6
References
– Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
CAS Number
– 1225383-33-4
Molecular Weight
– C31H34N2O6
Compound Purity
– 0.9886
SMILES
– CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O
Target
– Apoptosis|||c-Met/HGFR
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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