Products Details

Product Description

– E3 ligase Ligand 14 binds to E3 ubiquitin ligase and, when conjugated to a protein ligand via a linker, forms PROTACs that facilitate the ubiquitination-mediated degradation of cancer-promoting proteins[1].

Web ID

– T17872

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C38H52N4O7

References

– Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

CAS Number

– 2241489-43-8

Molecular Weight

– C38H52N4O7

SMILES

– C([C@@H](NC([C@@H](N(C(OC(C)(C)C)=O)C)C)=O)[C@H]1CCCCC1)(=O)N2[C@H](C(N[C@H]3C=4C(CCC3)=CC=CC4)=O)C[C@H](OC5=CC(O)=CC=C5)C2

Target

– MALT

Pathway

– Others

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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