ATRA-hydroxyimino
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ATRA-hydroxyimino

SKU T17733-100 mg Category Brand:

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Products Details

Product Description

– ATRA-hydroxyimino, also known as CRABP-II ligand 1, is a chemical compound derived from Retinoic acid (ATRA). This compound binds to the cIAP1 ligand, specifically Bestatin, through a linker, resulting in the formation of a complex called SNIPER. The purpose of this complex is to degrade CRABP-II within IMR-32 cells[1].

Web ID

– T17733

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H27NO3

References

– Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176.

CAS Number

– 135325-47-2

Molecular Weight

– C20H27NO3

SMILES

– C(=C/C(=C/C=C/C(=C/C(O)=O)/C)/C)C1=C(C)C(=NO)CCC1(C)C

Target

– Others

Pathway

– Others

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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