Download Files:
Mps1-IN-2
$94 – $900
Products Details
Product Description
– Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor, with an IC50 and a Kd of 145 nM and 12 nM for Mps1 and a Kd of 61 nM for Plk1.
Web ID
– HY-13994
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H36N6O3
References
– [1]Kwiatkowski N, et al. Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Nat Chem Biol. 2010 May;6(5):359-68.
CAS Number
– 1228817-38-6
Molecular Weight
– 480.60
Compound Purity
– 98.04
SMILES
– CN(C1=CN=C(NC2=C(OCC)C=C(N3CCC(O)CC3)C=C2)N=C1N(C4CCCC4)CC5)C5=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 13.33 mg/mL (ultrasonic)
Target
– Mps1;Polo-like Kinase (PLK)
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
