APN-PEG4-PFP

SKU T17452-100 mg Category Brand:

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Products Details

Product Description

– APN-PEG4-PFP is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Web ID

– T17452

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H25F5N2O7

References

– An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Weight

– C27H25F5N2O7

SMILES

– FC1=C(OC(CCOCCOCCOCCOCCNC(C2=CC=C(C#CC#N)C=C2)=O)=O)C(F)=C(F)C(F)=C1F

Target

– Reductase|||Estrogen Receptor/ERR|||Apoptosis

Pathway

– Others

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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