Vecabrutinib

SKU T17220-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 126 CAD through 1,555 CAD

Products Details

Product Description

– Vecabrutinib (SNS-062) is a potent, noncovalent inhibitor of BTK (Kd: 0.3 nM) and ITK (Kd: 2.2 nM), with an IC50 of 24 nM for ITK.

Web ID

– T17220

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H24ClF4N7O2

References

– Minke E. Binnerts, et al. Abstract C186: SNS-062 is a potent noncovalent BTK inhibitor with comparable activity against wild type BTK and BTK with an acquired resistance mutation. Molecular Cancer Therapeutics. December 2015 Volume 14, Issue 12 Supplement 2

CAS Number

– 1510829-06-7

Molecular Weight

– C22H24ClF4N7O2

Compound Purity

– 1

SMILES

– NC(=O)[C@H]1CCN(C[C@@H]1N1CCC[C@@H](Nc2cc(Cl)cc(c2)C(F)(F)F)C1=O)c1ncnc(N)c1F

Target

– PARP

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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