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PF-4989216
$126 – $840
Products Details
Product Description
– PF-4989216 is a potent and selective PI3Kα inhibitor with a Ki of 0.6 nM.
Web ID
– HY-13864
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C18H13FN6OS
References
– [1]Liu KK, et al. Highly Selective and Potent Thiophenes as PI3K Inhibitors with Oral Antitumor Activity. ACS Med Chem Lett. 2011 Sep 19;2(11):809-813.
CAS Number
– 1276553-09-3
Molecular Weight
– 380.40
Compound Purity
– 99.69
SMILES
– N#CC1=C(N2CCOCC2)SC(C3=NC=NN3)=C1C4=CC=C(C#N)C=C4F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 29 mg/mL
Target
– Apoptosis;PI3K
Isoform
– PI3Kα
Pathway
– Apoptosis;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
